| Factor | Molecular Weight | Functional Activity | Biologic Half-Life | Site of Production | Vitamin K Dependent | Plasma Concentration |
| Fibrinogen | 340,000 | --------- | 90 hrs. | Liver | No | 300-400mg/dL |
| Prothrombin | 72,000 | Serine Protease | 60 hrs. | Liver | Yes | 10-15 mg/dL |
| Factor V | 330,000 | Cofactor | 12-36 hrs. | Liver | No | 0.5-1.0 mg/dL |
| Factor VII | 48,000 | Serine Protease | 4-6 hrs. | Liver | Yes | 0.1 mg/dL |
| Factor VIII:C | 70-240,000 | Cofactor | 12 hrs. | Liver (?) | No | 1-2 mg/dL |
| Factor IX | 57,000 | Serine Protease | 20 hrs. | Liver | Yes | 4 µg/mL |
| Factor X | 58,000 | Serine Protease | 24 hrs. | Liver | Yes | 0.75 mg/dL |
| Factor XI | 160,000 | Serine Protease | 40 hrs. | Liver | No | 1.2 mg/dL |
| Factor XII | 80,000 | Serine Protease | 48-52 hrs. | Liver | No | 0.4 mg/dL |
| Prekallikrein | 80,000 | Serine Protease | 48-52 hrs. | Liver | No | 0.29 mg/dL |
| High Molecular Weight Kininogen | 120,000 | Cofactor | 6.5 days | Liver | No | 0.70 mg/dL |
| Factor XIII | 320,000 | Trans Glutaminase | 3-5 days | Liver | No | 2.5 mg/dL |
| Protein C | 62,000 | Serine Protease | 8-12 hrs. | Liver | Yes | 4-5 µg/mL |
| Protein S | 84,000 | Cofactor | -------- | Liver | Yes | 25 mg/L |
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